TY - JOUR AU - Buchon, Nicolas AU - Broderick, Nichole A. AU - Kuraishi, Takayuki AU - Lemaitre, Bruno PY - 2010 DA - 2010/12/22 TI - DrosophilaEGFR pathway coordinates stem cell proliferation and gut remodeling following infection JO - BMC Biology SP - 152 VL - 8 IS - 1 AB - Gut homeostasis is central to whole organism health, and its disruption is associated with a broad range of pathologies. Following damage, complex physiological events are required in the gut to maintain proper homeostasis. Previously, we demonstrated that ingestion of a nonlethal pathogen, Erwinia carotovora carotovora 15, induces a massive increase in stem cell proliferation in the gut of Drosophila. However, the precise cellular events that occur following infection have not been quantitatively described, nor do we understand the interaction between multiple pathways that have been implicated in epithelium renewal. SN - 1741-7007 UR - https://doi.org/10.1186/1741-7007-8-152 DO - 10.1186/1741-7007-8-152 ID - Buchon2010 ER -