| LNCaP-S14 |  | LNCaP |  | PC3 |  | DU145 |  | HeLa |  | IMR90 |  |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SMIP | p27 | p21 | p27 | p21 | p27 | p21 | p27 | p21 | p27 | p21 | p27 | p21 |
DMSO | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 |
SMIP001 | 1.9 ± 0.5 | 2.0 ± 0.6 | 1.5 ± 0.7 | 1.7 ± 0.6 | 1.3 ± 0.6 | 1.1 ± 0.5 | 1.1 ± 0.2 | 1.1 ± 0.3 | 1.1 ± 0.1 | 1.1 ± 0.2 | 1.0 ± 0.0 | 1.1 ± 0.0 |
SMIP004 | 2.4 ± 0.7 | 2.8 ± 0.7 | 2.1 ± 1.1 | 2.7 ± 0.1 | 1.1 ± 0.3 | 1.7 ± 0.9 | 1.3 ± 0.1 | 1.7 ± 0.5 | 1.1 ± 0.2 | 1.1 ± 0.1 | 1.2 ± 0.3 | 1.1 ± 0.0 |
MG132 | 1.5 |  | 1.9 ± 0.1 | 2.9 | 2.0 ± 1.0 | 4.1 ± 0.4 | 2.4 ± 0.1 | 3.1 | 2.2 ± 0.9 | 5.9 ± 1.7 | 0.9 ± 0.5 | 1.1 ± 0. 1 |
Bortezomib | 1.8 |  | 2.1 |  | 2.5 ± 1.0 | 4.7 ± 1.4 | 1.7 ± 0.5 | 2.5 ± 0.4 | 1.3 ± 0.2 | 2.2 ± 0.8 | 1.8 ± 0.0 | 1.8 ± 0.4 |