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Figure 2 | BMC Biology

Figure 2

From: Serious limitations of the QTL/Microarray approach for QTL gene discovery

Figure 2

Allelic bias in probe-level intensity. Fold change for average intensity from samples of the C57 background genotype over the average from samples of the CAST congenic genotype is shown in log2 scale for congenic strains in chromosomes 2 (HG2D), 11 (HG11) and 17 (HG17). (a) Probes are separated by genomic location for genes within donor congenic region and genes in the background genome. (b) Probes are separated in to those that overlap at least one known SNP (has SNP) from those that do not (no SNP). (c) Plots in (a) after removing probes in donor region with SNP. P values for difference between groups are shown above each graph.

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