TY - JOUR AU - Blair, Helen J. AU - Tompson, Stuart AU - Liu, Yu-Ning AU - Campbell, Jennifer AU - MacArthur, Katie AU - Ponting, Chris P. AU - Ruiz-Perez, Victor L. AU - Goodship, Judith A. PY - 2011 DA - 2011/02/28 TI - Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus JO - BMC Biology SP - 14 VL - 9 IS - 1 AB - Evc is essential for Indian Hedgehog (Hh) signalling in the cartilage growth plate. The gene encoding Evc2 is in close proximity in divergent orientation to Evc and mutations in both human genes lead to the chondrodysplasia Ellis-van Creveld syndrome. SN - 1741-7007 UR - https://doi.org/10.1186/1741-7007-9-14 DO - 10.1186/1741-7007-9-14 ID - Blair2011 ER -