Figure 3

Possible mode of IF assembly. Hypothetic model of the 3 nm “head-to-tail” overlap of two consecutive dimers as proposed for lamin dimers (adapted from [8]). This overlap engages both IF consensus motif 1 and IF consensus motif 2 from two dimeric chains as concluded from chemical crosslinking data and measurements of lamin head-to-tail dimer chains and paracrystals (for details see [1, 10]).