Necrotic lesions on leaves grown at non-permissive temperature. Rice leaves overexpressing NRKe, a gene encoding a kinase related to known disease-resistance kinases that induce necrosis in response to infection, are grown for 10 days at 24°C (the two blades on the left) and then for 3 days at 35°C (the two blades on the right). At 35°C, the non-permissive temperature, the leaves develop necrotic lesions. Taken from Figure 2b of Zhang et al. .