Examples of transcription factors mapping to different chromatin domains. YY1 has a preference for annotated promoters compared to the other factors. GATA2 maps to both methylated lysine 4 on histone H3 (H3K4me3) and H3K4me1, but not to annotated promoters, whereas NFE2 has a higher preference for H3K4me1. CTCF maps to open chromatin in addition to H3K4me1 and H3K4me3, whereas SETDB1 does not map well to any domain. As expected, none of the factors mapped well to domains containing the repressive H3K27me3 mark.