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Figure 9 | BMC Biology

Figure 9

From: Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements

Figure 9

Transcript and enhancer clusters show different overlap with histone modifications and open chromatin (OCR). Transcript clusters generally show a good overlap with all modification marks for accessible chromatin together with OCR, whereas enhancer clusters have a preference for methylated lysine 4 on histone H3 (H3K4me1) over H3K4me3 and acetylated lysine 27 on histone 3 (H3K27ac). The acetyltransferase p300 did not show a strong preference for enhancer clusters in Gm12878.

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BMC Biology

ISSN: 1741-7007

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