Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination

Table 1 Breakpoint coordinates and affected genes of molecularly confirmed HERV-HERV CNVs

Patient	Locus	Type	Coordinates^b	Size	RefSeq genes	Start maximum	Start minimum	Stop minimum	Stop maximum
1	1q41	Del	chr1:222146420-223203497	1.05 Mb	HHIPL2, TAF1A, MIA3, AIDA, BROX, FAM177B, DISP1	222150405	222150567	223201703	223201865
2	1q41	Del	chr1:222146420-223203497	1.05 Mb	HHIPL2, TAF1A, MIA3, AIDA, BROX, FAM177B, DISP1	222150567	222150621	223201865	223201919
3	2p12	Dup	chr2:75440857-76806830	1.36 Mb	FAM176A, GCFC2, MRPL19, GCFC2	75444928	75444972	76804990	76805034
4^a	2p12	Del	chr2:77315373-78197976	877 kb	LRRTM4, SNAR-H	77318677	77318740	78195410	78195473
5^a		Del				77318677	77318740	78195410	78195473
6		Del				77318421	77318561	78195154	78195294
7		Dup				77318269	77318318	78195002	78195051
8	11q24.3	Del	chr11:130434282-130629032	189 kb	C11orf44	130434794	130434845	130623915	130623967
9		Del				130434721	130434729	130623842	130623850
10		Dup				130434903	130434960	130624026	130624082

ISSN: 1741-7007