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Figure 10 | BMC Biology

Figure 10

From: The comprehensive analysis of DEG/ENaC subunits in Hydrareveals a large variety of peptide-gated channels, potentially involved in neuromuscular transmission

Figure 10

Diminazene is a potent inhibitor of HyNaCs. A) Current trace illustrating the concentration-dependent inhibition of HyNaC2/9/7 by diminazene. Block by 100 μM amiloride was used to compare the affinity for diminazene and amiloride. Note that current amplitude transiently increased after washout of the blockers. Dashed lines represent the zero current level. B) Concentration-response curves showing the concentration-dependent inhibition of HyNaCs by diminazene. HyNaCs, Hydra Na+ channels.

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BMC Biology

ISSN: 1741-7007

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