Figure 2From: A comprehensive evaluation of rodent malaria parasite genomes and gene expressionGene expression (RNAseq) in multiple RMP life cycle stages. A) Spearman correlation of FPKM values of orthologous genes between life cycle stages of PbA, PcAS and PyYM. PbA: ring (RI), trophozoite (Tr), schizont (Sch), gametocyte (Gct) and 16 and 24 hour ookinetes (Ook). PcAS: trophozoites (trophozoites of blood (Pc-bl)-and vector-transmitted (Pc-vec) PcAS; PyYM; blood stages (2 lines PyYM_WT and PyYM_MUT). B) Heat maps of expression (FPKM normalized by gene) of PbA genes in different life cycle stages. Left panel, all PbA genes ordered based on P. berghei expression pattern (FPKM values >21; in total 4,733 genes). Right panel, 2,236 PbA genes with orthologs in P. falciparum and FPKM values >63, ordered according to the temporal expression levels (in asexual blood stages) of their P. falciparum orthologs as shown in [34]. FPKM, fragments per kilo base of exon per million fragments mapped; RMP, rodent malaria parasites.Back to article page