Figure 1.
From: Frugal fat or munificent muscle: genomic imprinting and metabolism
Antagonistic effects of Grb10 and Dlk1. (a) Maternally expressed Grb10 and paternally expressed Dlk1 have opposing effects on fetal growth, fat mass and muscle fat. (b) Inactivation of Dlk1 results in low birth weight and muscle mass but high fat mass and blood glucose. (c) Inactivation of Grb10 results in the opposite set of phenotypes.