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Figure 8 | BMC Biology

Figure 8

From: Dawn- and dusk-phased circadian transcription rhythms coordinate anabolic and catabolic functions in Neurospora

Figure 8

Model of dawn- and dusk-phased transcription regulation. Genes activated by the WCC are transcribed predominantly during subjective late night to early morning where the activity of WCC is high. The activity of other transcription factors (TFs) including CSP1 could modulate the exact phase and the amplitude of these dawn-phased genes. These dawn-specific genes are mainly involved in energy harvesting and cell rescue. The phases of CSP1 repressed genes are enriched around dusk. Yet unidentified TFs must be involved in rhythmic activation of these genes since the phase and amplitude, but not the rhythmic expression of tested genes, were affected in ∆csp1. Our data suggest that expression of these TFs could be under the control of WCC. Dusk-phased genes are involved in energy utilization and growth, indicating a temporal distinction of cellular pathways and functions coordinated by the circadian clock of Neurospora.

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