TY - JOUR AU - Rostant, Wayne G. AU - Kay, Caroline AU - Wedell, Nina AU - Hosken, David J. PY - 2015 DA - 2015/06/29 TI - Sexual conflict maintains variation at an insecticide resistance locus JO - BMC Biology SP - 34 VL - 13 IS - 1 AB - The maintenance of genetic variation through sexually antagonistic selection is controversial, partly because specific sexually-antagonistic alleles have not been identified. The Drosophila DDT resistance allele (DDT-R) is an exception. This allele increases female fitness, but simultaneously decreases male fitness, and it has been suggested that this sexual antagonism could explain why polymorphism was maintained at the locus prior to DDT use. We tested this possibility using a genetic model and then used evolving fly populations to test model predictions. SN - 1741-7007 UR - https://doi.org/10.1186/s12915-015-0143-3 DO - 10.1186/s12915-015-0143-3 ID - Rostant2015 ER -