Fig. 3From: Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung developmentDynamic changes of abnormal lung structure in Apc CKO lungs. There was no significant histological difference in E11.5 lungs between WT and Apc CKO mice. Aggregative growth of mesenchymal cells in Apc CKO lungs was apparent from E12.5. Lung tissue (arrowheads) was interspersed with massive areas of hemorrhage at E14.5Back to article page