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Fig. 7 | BMC Biology

Fig. 7

From: Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body

Fig. 7

Summary of photoperiodic modulation of phase relationships among tissues in the circadian system. Phase relationships among tissues indicated by the ZT peak time of PER2 expression. Lines connect the same tissue collected from mice entrained to LD12:12 (top) versus LD20:4 (bottom). ZT peak time was determined using PER2::LUC for the adrenal gland (ADR), anterior pituitary gland (APIT), brown adipose tissue (BAT), cornea (CORN), esophagus (ESO), epididymal white adipose tissue (EWAT), inguinal white adipose tissue (IWAT), kidney (KID), liver (LIV), lung (LNG), mesenteric white adipose tissue (MWAT), pineal gland (PIN), posterior pituitary gland (PPIT), retina (RET), retinal pigmented epithelium (RPE), retroperitoneal white adipose tissue (RWAT), spleen (SPLN), and thymus (THY). ZT peak time was determined using PER2 immunohistochemistry for regions of the hippocampus (CA1, CA3, DG, Hilus) and septum (LS, MS)

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