Advertisement
Table 2 Data collection and refinement statistics for the GDF-5 R57A:BMPR-IA complex structure
| Processing | |
|---|---|
| Space group | I2 |
| Unit cell | a = 63.81 Å, b = 62.85 Å, c = 124.99 Å α = γ = 90 °, β = 95.85 ° |
| Wavelength (Å) | 1.5418 |
| Resolution (Å) | 24.0–2.28 (2.40–2.28) |
| No. reflections | 51,824 (7,550) |
| No. unique reflections | 22,044 (3,177) |
| Rmerge | 0.066 (0.384) |
| <(I)/σ (I)> | 7.4 (2.0) |
| Completeness (%) | 97.8 (97.4) |
| Redundancy | 2.4 (2.4) |
| Refinement | |
| Resolution (Å) | 23.8–2.28 (2.34–2.28) |
| R work/R free (%) | 19.7 (25.8)/24.1 (34.4) |
| Correlation coefficient (Fobs-Fcalc)free | 0.938 |
| Coordinate error (ESU) based Rfree | 0.218 Å |
| Number atoms | |
| Protein | 3,015 |
| Water | 93 |
| R.m.s. deviations | |
| Bond length (Å) | 0.013 |
| Bond angles (°) | 1.457 |
| Torsion angles (°)b | 8.345 |
| Torsion angles (°)c | 19.839 |
| TLS | 4 groups GDF-5 R57A (chain A + C, residues 11–115, 10–115) BMPR-IA (chain B + D, residues 31–118, 31–119) |
| Ramachandran analysisd | |
| Number of residues in favored region | 363 (95.5 %) |
| Number of residues in allowed region | 16 (4.2 %) |
| Number of residues in outlier region | 1 (0.3 %) |
