Fig. 2
From: Quantitative framework for ordered degradation of APC/C substrates
A dynamic model for substrate degradation. a The components of the model. A: free APC/CCdc20, S: free substrate, AS: APC/CCdc20-substrate complex, k a : association rate constant, k d : dissociation rate constant, k c : catalytic rate constant, e: degradation rate constant, p A : accumulation rate of active APC/CCdc20. See Additional file 1: Figure S4 for equations. b An example of a degradation profile of a substrate at one parameter set. APC/C anaphase-promoting complex/cyclosome