TY - JOUR AU - Snyder, Joshua C. AU - Pack, Thomas F. AU - Rochelle, Lauren K. AU - Chakraborty, Subhasish K. AU - Zhang, Ming AU - Eaton, Andrew W. AU - Bai, Yushi AU - Ernst, Lauren A. AU - Barak, Larry S. AU - Waggoner, Alan S. AU - Caron, Marc G. PY - 2015 DA - 2015/12/17 TI - A rapid and affordable screening platform for membrane protein trafficking JO - BMC Biology SP - 107 VL - 13 IS - 1 AB - Membrane proteins regulate a diversity of physiological processes and are the most successful class of targets in drug discovery. However, the number of targets adequately explored in chemical space and the limited resources available for screening are significant problems shared by drug-discovery centers and small laboratories. Therefore, a low-cost and universally applicable screen for membrane protein trafficking was developed. SN - 1741-7007 UR - https://doi.org/10.1186/s12915-015-0216-3 DO - 10.1186/s12915-015-0216-3 ID - Snyder2015 ER -