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Fig. 6 | BMC Biology

Fig. 6

From: iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function

Fig. 6

Distribution of differentially expressed purine-rich trimer exons following SAFB1 knockdown. Bar graphs showing the proportion of exons that contain the trimers of interest at particular locations in upregulated (top) and downregulated (bottom) exons compared to controls. The table shows the most significant motif pairs found in the last 50 nt of downregulated alternative exons for the three trimers (AAG, AGA and GAA) along with degenerate pairs defined as a specific target trimer paired with AAG, AAG or AGA (Any). Shown are the most highly significant pairings over-represented in downregulated exons, (from most to least significant). Bootstrapping with 10,000 samples yielded the estimated false discovery rates

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