Fig. 18

Relative enzyme π-elasticity coefficients. The π-elasticity coefficients (defined in Equation 4) with respect to protein abundance (blue), reactants (brown), allosteric effectors (pink), and reversible phosphorylation (green) for fasted hepatocytes at 4 mM plasma glucose (a) and fed hepatocytes at 10 mM plasma glucose (b). The elasticity coefficients for each enzyme were normalized to their absolute sum. For the reference flux values see legend of Table 3