TY - BOOK AU - Leffall, L. AU - Kripke, M. PY - 2010 DA - 2010// TI - President’s Cancer Panel: 2008–2009 Annual Report. Reducing Environmental Cancer Risk PB - National Cancer Institute CY - Bethseda, MD ID - Leffall2010 ER - TY - JOUR AU - Benigni, R. AU - Bossa, C. PY - 2011 DA - 2011// TI - Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology JO - Chem Rev VL - 111 UR - https://doi.org/10.1021/cr100222q DO - 10.1021/cr100222q ID - Benigni2011 ER - TY - JOUR AU - Rudel, R. A. AU - Fenton, S. E. AU - Ackerman, J. M. AU - Euling, S. Y. AU - Makris, S. L. PY - 2011 DA - 2011// TI - Environmental exposures and mammary gland development: state of the science, public health implications, and research recommendations JO - Environ Health Perspect VL - 119 UR - https://doi.org/10.1289/ehp.1002864 DO - 10.1289/ehp.1002864 ID - Rudel2011 ER - TY - JOUR AU - Williams, D. E. PY - 2012 DA - 2012// TI - The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention JO - Comp Biochem Physiol C Toxicol Pharmacol VL - 155 UR - https://doi.org/10.1016/j.cbpc.2011.05.013 DO - 10.1016/j.cbpc.2011.05.013 ID - Williams2012 ER - TY - JOUR AU - Mordukhovich, I. AU - Rossner, P. AU - Terry, M. B. AU - Santella, R. AU - Zhang, Y. J. AU - Hibshoosh, H. PY - 2010 DA - 2010// TI - Associations between polycyclic aromatic hydrocarbon-related exposures and p53 mutations in breast tumors JO - Environ Health Perspect VL - 118 UR - https://doi.org/10.1289/ehp.0901233 DO - 10.1289/ehp.0901233 ID - Mordukhovich2010 ER - TY - JOUR AU - Brody, J. G. AU - Moysich, K. B. AU - Humblet, O. AU - Attfield, K. R. AU - Beehler, G. P. AU - Rudel, R. A. PY - 2007 DA - 2007// TI - Environmental pollutants and breast cancer: epidemiologic studies JO - Cancer VL - 109 UR - https://doi.org/10.1002/cncr.22655 DO - 10.1002/cncr.22655 ID - Brody2007 ER - TY - JOUR AU - Eldrige, S. G. AU - Gould, M. N. AU - Butterworth, B. E. PY - 2006 DA - 2006// TI - Genotoxicity of environmental agents in human mammary epithelial cells JO - Cancer Res. VL - 4329 ID - Eldrige2006 ER - TY - JOUR AU - Kewley, R. J. AU - Whitelaw, M. L. AU - Chapman-Smith, A. PY - 2004 DA - 2004// TI - The mammalian basic helix–loop–helix/PAS family of transcriptional regulators JO - Int J Biochem Cell Biol VL - 36 UR - https://doi.org/10.1016/S1357-2725(03)00211-5 DO - 10.1016/S1357-2725(03)00211-5 ID - Kewley2004 ER - TY - JOUR AU - Furness, S. G. B. AU - Whelan, F. PY - 2009 DA - 2009// TI - The pleiotropy of dioxin toxicity — Xenobiotic misappropriation of the aryl hydrocarbon receptor & alternative physiological roles JO - Pharmacol Ther VL - 124 UR - https://doi.org/10.1016/j.pharmthera.2009.09.004 DO - 10.1016/j.pharmthera.2009.09.004 ID - Furness2009 ER - TY - JOUR AU - Schlezinger, J. J. AU - Liu, D. AU - Farago, M. AU - Seldin, D. C. AU - Belguise, K. AU - Sonenshein, G. E. PY - 2006 DA - 2006// TI - A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis JO - Biol Chem VL - 387 UR - https://doi.org/10.1515/BC.2006.145 DO - 10.1515/BC.2006.145 ID - Schlezinger2006 ER - TY - JOUR AU - Safe, S. AU - Lee, S. O. AU - Jin, U. H. PY - 2013 DA - 2013// TI - Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target JO - Toxicol Sci VL - 135 UR - https://doi.org/10.1093/toxsci/kft128 DO - 10.1093/toxsci/kft128 ID - Safe2013 ER - TY - JOUR AU - Brooks, J. AU - Eltom, S. PY - 2011 DA - 2011// TI - Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptor JO - Curr Cancer Drug Targets. VL - 11 UR - https://doi.org/10.2174/156800911795655967 DO - 10.2174/156800911795655967 ID - Brooks2011 ER - TY - JOUR AU - Goode, G. D. AU - Ballard, B. R. AU - Manning, H. C. AU - Freeman, M. L. AU - Kang, Y. AU - Eltom, S. E. PY - 2013 DA - 2013// TI - Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line JO - Int J Cancer VL - 133 ID - Goode2013 ER - TY - JOUR AU - Goode, G. AU - Pratap, S. AU - Eltom, S. E. PY - 2014 DA - 2014// TI - Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expression of genes in key regulatory pathways of cancer JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0100103 DO - 10.1371/journal.pone.0100103 ID - Goode2014 ER - TY - JOUR AU - Yang, X. AU - Solomon, S. AU - Fraser, L. R. AU - Trombino, A. F. AU - Liu, D. AU - Sonenshein, G. E. PY - 2008 DA - 2008// TI - Constitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissue JO - J Cell Biochem VL - 104 UR - https://doi.org/10.1002/jcb.21630 DO - 10.1002/jcb.21630 ID - Yang2008 ER - TY - JOUR AU - Chang, C. AU - Puga, A. PY - 1998 DA - 1998// TI - Constitutive activation of the aromatic hydrocarbon receptor JO - Mol Cell Biol VL - 18 UR - https://doi.org/10.1128/MCB.18.1.525 DO - 10.1128/MCB.18.1.525 ID - Chang1998 ER - TY - JOUR AU - Opitz, C. A. AU - Litzenburger, U. M. AU - Sahm, F. AU - Ott, M. AU - Tritschler, I. AU - Trump, S. PY - 2011 DA - 2011// TI - An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor JO - Nature VL - 478 UR - https://doi.org/10.1038/nature10491 DO - 10.1038/nature10491 ID - Opitz2011 ER - TY - JOUR AU - Al-Hajj, M. AU - Wicha, M. S. AU - Benito-Hernandez, A. AU - Morrison, S. AU - Clarke, M. F. PY - 2003 DA - 2003// TI - Prospective identification of tumorigenic breast cancer cells JO - Proc Nat Acad Sci VL - 100 UR - https://doi.org/10.1073/pnas.0530291100 DO - 10.1073/pnas.0530291100 ID - Al-Hajj2003 ER - TY - JOUR AU - Charafe-Jauffret, E. AU - Ginestier, C. AU - Iovino, F. AU - Tarpin, C. AU - Diebel, M. AU - Esterni, B. PY - 2010 DA - 2010// TI - Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-1630 DO - 10.1158/1078-0432.CCR-09-1630 ID - Charafe-Jauffret2010 ER - TY - JOUR AU - Charafe-Jauffret, E. AU - Ginestier, C. AU - Iovino, F. AU - Wicinski, J. AU - Cervera, N. AU - Finetti, P. PY - 2009 DA - 2009// TI - Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature JO - Cancer Res VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-08-2741 DO - 10.1158/0008-5472.CAN-08-2741 ID - Charafe-Jauffret2009 ER - TY - JOUR AU - Economopoulou, P. AU - Kaklamani, V. G. AU - Siziopikou, K. PY - 2012 DA - 2012// TI - The role of cancer stem cells in breast cancer initiation and progression: potential cancer stem cell-directed therapies JO - Oncologist VL - 17 UR - https://doi.org/10.1634/theoncologist.2012-0163 DO - 10.1634/theoncologist.2012-0163 ID - Economopoulou2012 ER - TY - JOUR AU - Gangopadhyay, S. AU - Nandy, A. AU - Hor, P. AU - Mukhopadhyay, A. PY - 2013 DA - 2013// TI - Breast cancer stem cells: A novel therapeutic target JO - Clin Breast Cancer VL - 13 UR - https://doi.org/10.1016/j.clbc.2012.09.017 DO - 10.1016/j.clbc.2012.09.017 ID - Gangopadhyay2013 ER - TY - JOUR AU - Ginestier, C. AU - Hur, M. -. H. AU - Charafe-Jauffret, E. AU - Monville, F. AU - Dutcher, J. AU - Brown, M. PY - 2007 DA - 2007// TI - ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome JO - Cell Stem Cell VL - 1 UR - https://doi.org/10.1016/j.stem.2007.08.014 DO - 10.1016/j.stem.2007.08.014 ID - Ginestier2007 ER - TY - JOUR AU - Lobo, N. A. AU - Shimono, Y. AU - Qian, D. AU - Clarke, M. F. PY - 2007 DA - 2007// TI - The biology of cancer stem cells JO - Ann Rev Cell Dev Biol VL - 23 UR - https://doi.org/10.1146/annurev.cellbio.22.010305.104154 DO - 10.1146/annurev.cellbio.22.010305.104154 ID - Lobo2007 ER - TY - JOUR AU - Fischer, K. R. AU - Durrans, A. AU - Lee, S. AU - Sheng, J. AU - Li, F. AU - Wong, S. T. PY - 2015 DA - 2015// TI - Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance JO - Nature VL - 527 UR - https://doi.org/10.1038/nature15748 DO - 10.1038/nature15748 ID - Fischer2015 ER - TY - JOUR AU - Bolós, V. AU - Blanco, M. AU - Medina, V. AU - Aparicio, G. AU - Díaz-Prado, S. AU - Grande, E. PY - 2009 DA - 2009// TI - Notch signalling in cancer stem cells JO - Clin Transl Oncol VL - 11 UR - https://doi.org/10.1007/s12094-009-0305-2 DO - 10.1007/s12094-009-0305-2 ID - Bolós2009 ER - TY - JOUR AU - Leis, O. AU - Eguiara, A. AU - Lopez-Arribillaga, E. AU - Alberdi, M. J. AU - Hernandez-Garcia, S. AU - Elorriaga, K. PY - 2011 DA - 2011// TI - Sox2 expression in breast tumours and activation in breast cancer stem cells JO - Oncogene VL - 31 UR - https://doi.org/10.1038/onc.2011.338 DO - 10.1038/onc.2011.338 ID - Leis2011 ER - TY - JOUR AU - Mani, S. A. AU - Guo, W. AU - Liao, M. -. J. AU - Eaton, E. N. AU - Ayyanan, A. AU - Zhou, A. Y. PY - 2008 DA - 2008// TI - The epithelial-mesenchymal transition generates cells with properties of stem cells JO - Cell VL - 133 UR - https://doi.org/10.1016/j.cell.2008.03.027 DO - 10.1016/j.cell.2008.03.027 ID - Mani2008 ER - TY - JOUR AU - Scheel, C. AU - Weinberg, R. A. PY - 2012 DA - 2012// TI - Cancer stem cells and epithelial–mesenchymal transition: concepts and molecular links JO - Semin Cancer Biol VL - 22 UR - https://doi.org/10.1016/j.semcancer.2012.04.001 DO - 10.1016/j.semcancer.2012.04.001 ID - Scheel2012 ER - TY - JOUR AU - Chiou, S. H. AU - Wang, M. L. AU - Chou, Y. T. AU - Chen, C. J. AU - Hong, C. F. AU - Hsieh, W. J. PY - 2010 DA - 2010// TI - Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-10-2638 DO - 10.1158/0008-5472.CAN-10-2638 ID - Chiou2010 ER - TY - JOUR AU - Wicha, M. AU - Dontu, G. AU - Al-Hajj, M. PY - 2003 DA - 2003// TI - Stem cells in normal breast development and breast cancer JO - Cell Prolif. VL - 36 UR - https://doi.org/10.1046/j.1365-2184.36.s.1.6.x DO - 10.1046/j.1365-2184.36.s.1.6.x ID - Wicha2003 ER - TY - JOUR AU - Tanei, T. AU - Morimoto, K. AU - Shimazu, K. AU - Kim, S. J. AU - Tanji, Y. AU - Taguchi, T. PY - 2009 DA - 2009// TI - Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential paclitaxel and epirubicin-based chemotherapy for breast cancers JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-1479 DO - 10.1158/1078-0432.CCR-08-1479 ID - Tanei2009 ER - TY - JOUR AU - Reya, T. AU - Morrison, S. J. AU - Clarke, M. F. AU - Weissman, I. L. PY - 2001 DA - 2001// TI - Stem cells, cancer, and cancer stem cells JO - Nature. VL - 414 UR - https://doi.org/10.1038/35102167 DO - 10.1038/35102167 ID - Reya2001 ER - TY - JOUR AU - Gasiewicz, T. A. AU - Singh, K. P. AU - Bennett, J. A. PY - 2014 DA - 2014// TI - The Ah receptor in stem cell cycling, regulation, and quiescence JO - Ann N Y Acad Sci VL - 1310 UR - https://doi.org/10.1111/nyas.12361 DO - 10.1111/nyas.12361 ID - Gasiewicz2014 ER - TY - JOUR AU - Ko, C. -. I. AU - Wang, Q. AU - Fan, Y. AU - Xia, Y. AU - Puga, A. PY - 2014 DA - 2014// TI - Pluripotency factors and Polycomb Group proteins repress aryl hydrocarbon receptor expression in murine embryonic stem cells JO - Stem Cell Res VL - 12 UR - https://doi.org/10.1016/j.scr.2013.11.007 DO - 10.1016/j.scr.2013.11.007 ID - Ko2014 ER - TY - JOUR AU - Singh, K. P. AU - Bennett, J. A. AU - Casado, F. L. AU - Walrath, J. L. AU - Welle, S. L. AU - Gasiewicz, T. A. PY - 2014 DA - 2014// TI - Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice JO - Stem Cells Dev VL - 23 UR - https://doi.org/10.1089/scd.2013.0346 DO - 10.1089/scd.2013.0346 ID - Singh2014 ER - TY - JOUR AU - Singh, K. P. AU - Garrett, R. W. AU - Casado, F. L. AU - Gasiewicz, T. A. PY - 2011 DA - 2011// TI - Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions JO - Stem Cells Dev VL - 20 UR - https://doi.org/10.1089/scd.2010.0333 DO - 10.1089/scd.2010.0333 ID - Singh2011 ER - TY - JOUR AU - Wang, Q. AU - Chen, J. AU - Ko, C. -. I. AU - Fan, Y. AU - Carreira, V. AU - Chen, Y. PY - 2013 DA - 2013// TI - Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis JO - Environ Health Perspect VL - 121 ID - Wang2013 ER - TY - JOUR AU - Smith, B. W. AU - Rozelle, S. S. AU - Leung, A. AU - Ubellacker, J. AU - Parks, A. AU - Nah, S. K. PY - 2013 DA - 2013// TI - The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation JO - Blood VL - 122 UR - https://doi.org/10.1182/blood-2012-11-466722 DO - 10.1182/blood-2012-11-466722 ID - Smith2013 ER - TY - JOUR AU - Latchney, S. AU - Lioy, D. AU - Henry, E. AU - Gasiewicz, T. A. AU - Strathmann, F. AU - Mayer-Proschel, M. PY - 2011 DA - 2011// TI - Neural precursor cell proliferation Is disrupted through activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin JO - Stem Cells Dev. VL - 20 UR - https://doi.org/10.1089/scd.2009.0529 DO - 10.1089/scd.2009.0529 ID - Latchney2011 ER - TY - JOUR AU - Abdelrahim, M. AU - Smith, R. AU - Safe, S. PY - 2003 DA - 2003// TI - Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells JO - Mol Pharmacol VL - 63 UR - https://doi.org/10.1124/mol.63.6.1373 DO - 10.1124/mol.63.6.1373 ID - Abdelrahim2003 ER - TY - JOUR AU - Parks, A. J. AU - Pollastri, M. P. AU - Hahn, M. E. AU - Stanford, E. A. AU - Novikov, O. AU - Franks, D. G. PY - 2014 DA - 2014// TI - In silico identification of an aryl hydrocarbon receptor (AHR) antagonist with biological activity in vitro and in vivo JO - Mol Pharmacol VL - 86 UR - https://doi.org/10.1124/mol.114.093369 DO - 10.1124/mol.114.093369 ID - Parks2014 ER - TY - JOUR AU - Quadri, S. AU - Qadri, A. AU - Hahn, M. AU - Mann, K. AU - Sherr, D. PY - 2000 DA - 2000// TI - The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis JO - Mol Pharmacol VL - 58 ID - Quadri2000 ER - TY - JOUR AU - Trombino, A. AU - Near, R. AU - Matulka, R. A. AU - Yang, S. AU - Hafer, L. AU - Toselli, P. PY - 2000 DA - 2000// TI - Expression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 JO - Breast Cancer Res Treat. VL - 63 UR - https://doi.org/10.1023/A:1006443104670 DO - 10.1023/A:1006443104670 ID - Trombino2000 ER - TY - JOUR AU - Murray, S. A. AU - Yang, S. AU - Demicco, E. AU - Ying, H. AU - Sherr, D. H. AU - Hafer, L. J. PY - 2005 DA - 2005// TI - Increased expression of MDM2, cyclin D1, and p27(Kip1) in carcinogen-induced rat mammary tumors JO - J Cell Biochem VL - 95 UR - https://doi.org/10.1002/jcb.20414 DO - 10.1002/jcb.20414 ID - Murray2005 ER - TY - JOUR AU - Currier, N. AU - Solomon, S. E. AU - Demicco, E. G. AU - Chang, D. L. AU - Farago, M. AU - Ying, H. PY - 2005 DA - 2005// TI - Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors JO - Toxicol Pathol VL - 33 UR - https://doi.org/10.1080/01926230500352226 DO - 10.1080/01926230500352226 ID - Currier2005 ER - TY - JOUR AU - Hall, J. M. AU - Barhoover, M. A. AU - Kazmin, D. AU - McDonnell, D. P. AU - Greenlee, W. F. AU - Thomas, R. S. PY - 2010 DA - 2010// TI - Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation JO - Mol Endocrinol VL - 24 UR - https://doi.org/10.1210/me.2009-0346 DO - 10.1210/me.2009-0346 ID - Hall2010 ER - TY - JOUR AU - Dalerba, P. AU - Cho, R. W. AU - Clarke, M. F. PY - 2007 DA - 2007// TI - Cancer stem cells: models and concepts JO - Annu Rev Med VL - 58 UR - https://doi.org/10.1146/annurev.med.58.062105.204854 DO - 10.1146/annurev.med.58.062105.204854 ID - Dalerba2007 ER - TY - JOUR AU - Magee, J. A. AU - Piskounova, E. AU - Morrison, S. J. PY - 2012 DA - 2012// TI - Cancer stem cells: impact, heterogeneity, and uncertainty JO - Cancer Cell VL - 21 UR - https://doi.org/10.1016/j.ccr.2012.03.003 DO - 10.1016/j.ccr.2012.03.003 ID - Magee2012 ER - TY - JOUR AU - Tang, B. AU - Raviv, A. AU - Esposito, D. AU - Flanders, K. C. AU - Daniel, C. AU - Nghiem, B. T. PY - 2015 DA - 2015// TI - A flexible reporter system for direct observation and isolation of cancer stem cells JO - Stem Cell Rep VL - 4 UR - https://doi.org/10.1016/j.stemcr.2014.11.002 DO - 10.1016/j.stemcr.2014.11.002 ID - Tang2015 ER - TY - JOUR AU - Visvader, J. E. AU - Lindeman, G. J. PY - 2012 DA - 2012// TI - Cancer stem cells: current status and evolving complexities JO - Cell Stem Cell VL - 10 UR - https://doi.org/10.1016/j.stem.2012.05.007 DO - 10.1016/j.stem.2012.05.007 ID - Visvader2012 ER - TY - JOUR AU - Croker, A. K. AU - Goodale, D. AU - Chu, J. AU - Postenka, C. AU - Hedley, B. D. AU - Hess, D. A. PY - 2009 DA - 2009// TI - High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability JO - J Cell Mol Med VL - 13 UR - https://doi.org/10.1111/j.1582-4934.2008.00455.x DO - 10.1111/j.1582-4934.2008.00455.x ID - Croker2009 ER - TY - JOUR AU - Croker, A. K. AU - Allan, A. L. PY - 2011 DA - 2011// TI - Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44+ human breast cancer cells JO - Breast Cancer Res Treat VL - 133 UR - https://doi.org/10.1007/s10549-011-1692-y DO - 10.1007/s10549-011-1692-y ID - Croker2011 ER - TY - JOUR AU - Choi, E. Y. AU - Lee, H. AU - Dingle, R. W. C. AU - Kim, K. B. AU - Swanson, H. I. PY - 2011 DA - 2011// TI - Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor JO - Mol Pharmacol VL - 81 UR - https://doi.org/10.1124/mol.111.073643 DO - 10.1124/mol.111.073643 ID - Choi2011 ER - TY - JOUR AU - Kim, S. H. AU - Henry, E. C. AU - Kim, D. K. AU - Kim, Y. H. AU - Shin, K. J. AU - Han, M. S. PY - 2006 DA - 2006// TI - Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-Induced toxicity by antagonizing the aryl hydrocarbon receptor JO - Mol Pharmacol VL - 69 UR - https://doi.org/10.1124/mol.105.021832 DO - 10.1124/mol.105.021832 ID - Kim2006 ER - TY - JOUR AU - Jönsson, M. AU - Franks, D. AU - Woodin, B. AU - Jenny, M. AU - Garrick, R. AU - Behrendt, L. PY - 2009 DA - 2009// TI - The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish JO - Chem Biol Interact VL - 181 UR - https://doi.org/10.1016/j.cbi.2009.07.003 DO - 10.1016/j.cbi.2009.07.003 ID - Jönsson2009 ER - TY - JOUR AU - Holliday, D. AU - Speirs, V. PY - 2011 DA - 2011// TI - Choosing the right cell line for breast cancer research JO - Breast Cancer Res VL - 13 ID - Holliday2011 ER - TY - JOUR AU - Chaffer, C. L. AU - Brueckmann, I. AU - Scheel, C. AU - Kaestli, A. J. AU - Wiggins, P. A. AU - Rodrigues, L. O. PY - 2011 DA - 2011// TI - Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state JO - Proc Nat Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1102454108 DO - 10.1073/pnas.1102454108 ID - Chaffer2011 ER - TY - JOUR AU - Watson, J. D. AU - Prokopec, S. D. AU - Smith, A. B. AU - Okey, A. B. AU - Pohjanvirta, R. AU - Boutros, P. C. PY - 2014 DA - 2014// TI - TCDD dysregulation of 13 AHR-target genes in rat liver JO - Toxicol Appl Pharmacol VL - 274 UR - https://doi.org/10.1016/j.taap.2013.12.004 DO - 10.1016/j.taap.2013.12.004 ID - Watson2014 ER - TY - JOUR AU - Forghanifard, M. M. AU - Ardalan Khales, S. AU - Javdani-Mallak, A. AU - Rad, A. AU - Farshchian, M. AU - Abbaszadegan, M. R. PY - 2014 DA - 2014// TI - Stemness state regulators SALL4 and SOX2 are involved in progression and invasiveness of esophageal squamous cell carcinoma JO - Med Oncol VL - 31 UR - https://doi.org/10.1007/s12032-014-0922-7 DO - 10.1007/s12032-014-0922-7 ID - Forghanifard2014 ER - TY - JOUR AU - Lengerke, C. AU - Fehm, T. AU - Kurth, R. AU - Neubauer, H. AU - Scheble, V. AU - Müller, F. PY - 2011 DA - 2011// TI - Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma JO - BMC Cancer. VL - 11 UR - https://doi.org/10.1186/1471-2407-11-42 DO - 10.1186/1471-2407-11-42 ID - Lengerke2011 ER - TY - JOUR AU - Liang, S. AU - Furuhashi, M. AU - Nakane, R. AU - Nakazawa, S. PY - 2013 DA - 2013// TI - Hamada J-i, Iizasa H. Isolation and characterization of human breast cancer cells with SOX2 promoter activity JO - Biochem Biophys Res Commun VL - 437 UR - https://doi.org/10.1016/j.bbrc.2013.06.038 DO - 10.1016/j.bbrc.2013.06.038 ID - Liang2013 ER - TY - JOUR AU - Rodriguez-Pinilla, S. M. AU - Sarrio, D. AU - Moreno-Bueno, G. AU - Rodriguez-Gil, Y. AU - Martinez, M. A. AU - Hernandez, L. PY - 2007 DA - 2007// TI - Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer JO - Mod Pathol VL - 20 UR - https://doi.org/10.1038/modpathol.3800760 DO - 10.1038/modpathol.3800760 ID - Rodriguez-Pinilla2007 ER - TY - JOUR AU - Ling, G. Q. AU - Chen, D. B. AU - Wang, B. Q. AU - Zhang, L. S. PY - 2012 DA - 2012// TI - Expression of the pluripotency markers Oct3/4, Nanog and Sox2 in human breast cancer cell lines JO - Oncol Lett VL - 4 ID - Ling2012 ER - TY - JOUR AU - Raimondi, C. AU - Gradilone, A. AU - Naso, G. AU - Vincenzi, B. AU - Petracca, A. AU - Nicolazzo, C. PY - 2011 DA - 2011// TI - Epithelial-mesenchymal transition and stemness features in circulating tumor cells from breast cancer patients JO - Breast Cancer Res Treat VL - 130 UR - https://doi.org/10.1007/s10549-011-1373-x DO - 10.1007/s10549-011-1373-x ID - Raimondi2011 ER - TY - JOUR AU - Barretina, J. AU - Caponigro, G. AU - Stransky, N. AU - Venkatesan, K. AU - Margolin, A. A. AU - Kim, S. PY - 2012 DA - 2012// TI - The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity JO - Nature VL - 483 UR - https://doi.org/10.1038/nature11003 DO - 10.1038/nature11003 ID - Barretina2012 ER - TY - JOUR AU - Shehin, S. E. AU - Stephenson, R. O. AU - Greenlee, W. F. PY - 2000 DA - 2000// TI - Transcriptional regulation of the human CYP1B1 gene. Evidence for involvement of an aryl hydrocarbon receptor response element in constitutive expression JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.275.10.6770 DO - 10.1074/jbc.275.10.6770 ID - Shehin2000 ER - TY - JOUR AU - Ma, C. X. AU - Ellis, M. J. PY - 2013 DA - 2013// TI - The Cancer Genome Atlas: clinical applications for breast cancer JO - Oncology VL - 27 ID - Ma2013 ER - TY - JOUR AU - Curtis, C. AU - Shah, S. P. AU - Chin, S. F. AU - Turashvili, G. AU - Rueda, O. M. AU - Dunning, M. J. PY - 2012 DA - 2012// TI - The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups JO - Nature VL - 486 ID - Curtis2012 ER - TY - JOUR AU - Dontu, G. AU - Wicha, M. S. PY - 2005 DA - 2005// TI - Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia JO - J Mammary Gland Biol Neoplasia VL - 10 UR - https://doi.org/10.1007/s10911-005-2542-5 DO - 10.1007/s10911-005-2542-5 ID - Dontu2005 ER - TY - JOUR AU - Ponti, D. AU - Zaffaroni, N. AU - Capelli, C. PY - 2006 DA - 2006// TI - Breast cancer stem cells: an overview JO - Eur J Cancer VL - 42 UR - https://doi.org/10.1016/j.ejca.2006.01.031 DO - 10.1016/j.ejca.2006.01.031 ID - Ponti2006 ER - TY - JOUR AU - Fillmore, C. M. AU - Kuperwasser, C. PY - 2008 DA - 2008// TI - Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy JO - Breast Cancer Res VL - 10 UR - https://doi.org/10.1186/bcr1982 DO - 10.1186/bcr1982 ID - Fillmore2008 ER - TY - JOUR AU - Li, H. Z. AU - Yi, T. B. AU - Wu, Z. Y. PY - 2008 DA - 2008// TI - Suspension culture combined with chemotherapeutic agents for sorting of breast cancer stem cells JO - BMC Cancer. VL - 8 UR - https://doi.org/10.1186/1471-2407-8-135 DO - 10.1186/1471-2407-8-135 ID - Li2008 ER - TY - JOUR AU - Gonzalez-Angulo, A. M. AU - Hennessy, B. T. AU - Broglio, K. AU - Meric-Bernstam, F. AU - Cristofanilli, M. AU - Giordano, S. H. PY - 2007 DA - 2007// TI - Trends for inflammatory breast cancer: is survival improving? JO - Oncologist VL - 12 UR - https://doi.org/10.1634/theoncologist.12-8-904 DO - 10.1634/theoncologist.12-8-904 ID - Gonzalez-Angulo2007 ER - TY - JOUR AU - Clevers, H. PY - 2011 DA - 2011// TI - The cancer stem cell: premises, promises and challenges JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2304 DO - 10.1038/nm.2304 ID - Clevers2011 ER - TY - JOUR AU - Qiu, M. AU - Peng, Q. AU - Jiang, I. AU - Carroll, C. AU - Han, G. AU - Rymer, I. PY - 2013 DA - 2013// TI - Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells JO - Cancer Lett VL - 328 UR - https://doi.org/10.1016/j.canlet.2012.09.023 DO - 10.1016/j.canlet.2012.09.023 ID - Qiu2013 ER - TY - JOUR AU - Bekki, K. AU - Vogel, H. AU - Li, W. AU - Ito, T. AU - Sweeney, C. AU - Haarmann-Stemmann, T. PY - 2015 DA - 2015// TI - The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells JO - Pestic Biochem Physiol. VL - 120 UR - https://doi.org/10.1016/j.pestbp.2014.12.021 DO - 10.1016/j.pestbp.2014.12.021 ID - Bekki2015 ER - TY - JOUR AU - Raha, D. AU - Wilson, T. R. AU - Peng, J. AU - Peterson, D. AU - Yue, P. AU - Evangelista, M. PY - 2014 DA - 2014// TI - The cancer stem cell marker aldehyde dehydrogenase is required to maintain a drug-tolerant tumor cell subpopulation JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-3456 DO - 10.1158/0008-5472.CAN-13-3456 ID - Raha2014 ER - TY - JOUR AU - Kim, D. W. AU - Gazourian, L. AU - Quadri, S. A. AU - Romieu-Mourez, R. AU - Sherr, D. H. AU - Sonenshein, G. E. PY - 2000 DA - 2000// TI - The RelA NF-κB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells JO - Oncogene VL - 19 UR - https://doi.org/10.1038/sj.onc.1203945 DO - 10.1038/sj.onc.1203945 ID - Kim2000 ER - TY - JOUR AU - Boitano, A. AU - Wang, J. AU - Romeo, R. AU - Bouchez, L. AU - Parker, A. AU - Sutton, S. PY - 2010 DA - 2010// TI - Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells JO - Science VL - 329 UR - https://doi.org/10.1126/science.1191536 DO - 10.1126/science.1191536 ID - Boitano2010 ER - TY - JOUR AU - Simmons, M. J. AU - Serra, R. AU - Hermance, N. AU - Kelliher, M. A. PY - 2012 DA - 2012// TI - NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere forming activity in vitro JO - Breast Cancer Res VL - 14 UR - https://doi.org/10.1186/bcr3321 DO - 10.1186/bcr3321 ID - Simmons2012 ER - TY - JOUR AU - Hombach-Klonisch, S. AU - Paranjothy, T. AU - Wiechec, E. AU - Pocar, P. AU - Mustafa, T. AU - Seifert, A. PY - 2008 DA - 2008// TI - Cancer stem cells as targets for cancer therapy: selected cancers as examples JO - Arch Immunol Ther Exp VL - 56 UR - https://doi.org/10.1007/s00005-008-0023-4 DO - 10.1007/s00005-008-0023-4 ID - Hombach-Klonisch2008 ER - TY - JOUR AU - Park, I. -. K. AU - Morrison, S. J. AU - Clarke, M. F. PY - 2004 DA - 2004// TI - Bmi1, stem cells, and senescence regulation JO - J Clin Investig VL - 113 UR - https://doi.org/10.1172/JCI200420800 DO - 10.1172/JCI200420800 ID - Park2004 ER - TY - JOUR AU - Paranjape, A. AU - Balaji, S. AU - Mandal, T. AU - Krushik, E. AU - Nagaraj, P. AU - Mukherjee, G. PY - 2014 DA - 2014// TI - Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog JO - BMC Cancer. VL - 14 UR - https://doi.org/10.1186/1471-2407-14-785 DO - 10.1186/1471-2407-14-785 ID - Paranjape2014 ER - TY - JOUR AU - Ezeh, U. I. AU - Turek, P. J. AU - Reijo, R. A. AU - Clark, A. T. PY - 2005 DA - 2005// TI - Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma JO - Cancer VL - 104 UR - https://doi.org/10.1002/cncr.21432 DO - 10.1002/cncr.21432 ID - Ezeh2005 ER - TY - JOUR AU - Takahashi, K. AU - Yamanaka, S. PY - 2006 DA - 2006// TI - Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors JO - Cell VL - 126 UR - https://doi.org/10.1016/j.cell.2006.07.024 DO - 10.1016/j.cell.2006.07.024 ID - Takahashi2006 ER - TY - JOUR AU - Battula, V. L. AU - Evans, K. W. AU - Hollier, B. G. AU - Shi, Y. AU - Marini, F. C. AU - Ayyanan, A. PY - 2010 DA - 2010// TI - Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells JO - Stem Cells VL - 28 UR - https://doi.org/10.1002/stem.467 DO - 10.1002/stem.467 ID - Battula2010 ER - TY - JOUR AU - Morel, A. -. P. AU - Lièvre, M. AU - Thomas, C. AU - Hinkal, G. AU - Ansieau, S. AU - Puisieux, A. PY - 2008 DA - 2008// TI - Generation of breast cancer stem cells through epithelial-mesenchymal transition JO - PLoS One VL - 3 UR - https://doi.org/10.1371/journal.pone.0002888 DO - 10.1371/journal.pone.0002888 ID - Morel2008 ER - TY - JOUR AU - Maecker, B. AU - Sherr, D. AU - Vonderheide, R. AU - Bergwelt-Baildon, M. AU - Hirano, N. AU - Anderson, K. PY - 2003 DA - 2003// TI - The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells JO - Blood VL - 102 UR - https://doi.org/10.1182/blood-2003-05-1374 DO - 10.1182/blood-2003-05-1374 ID - Maecker2003 ER - TY - JOUR AU - Shatalova, E. G. AU - Klein-Szanto, A. J. AU - Devarajan, K. AU - Cukierman, E. AU - Clapper, M. L. PY - 2011 DA - 2011// TI - Estrogen and cytochrome P450 1B1 contribute to both early- and late-stage head and neck carcinogenesis JO - Cancer Prev Res (Phila) VL - 4 UR - https://doi.org/10.1158/1940-6207.CAPR-10-0133 DO - 10.1158/1940-6207.CAPR-10-0133 ID - Shatalova2011 ER - TY - JOUR AU - Wincent, E. AU - Bengtsson, J. AU - Bardbori, A. AU - Alsberg, T. AU - Luecke, S. AU - Rannug, U. PY - 2012 DA - 2012// TI - Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor JO - PNAS VL - 109 UR - https://doi.org/10.1073/pnas.1118467109 DO - 10.1073/pnas.1118467109 ID - Wincent2012 ER - TY - JOUR AU - Barhoover, M. A. AU - Hall, J. M. AU - Greenlee, W. F. AU - Thomas, R. S. PY - 2010 DA - 2010// TI - Aryl hydrocarbon receptor regulates cell cycle progression in human breast cancer cells via a functional interaction with cyclin-dependent kinase 4 JO - Mol Pharmacol VL - 77 UR - https://doi.org/10.1124/mol.109.059675 DO - 10.1124/mol.109.059675 ID - Barhoover2010 ER - TY - JOUR AU - Chang, J. T. AU - Chang, H. AU - Chen, P. H. AU - Lin, S. L. AU - Lin, P. PY - 2007 DA - 2007// TI - Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-Regulation and cell growth in human lung adenocarcinomas JO - Clin Cancer Res VL - 13 UR - https://doi.org/10.1158/1078-0432.CCR-06-1166 DO - 10.1158/1078-0432.CCR-06-1166 ID - Chang2007 ER - TY - JOUR AU - Powell, J. B. AU - Goode, G. D. AU - Eltom, S. E. PY - 2013 DA - 2013// TI - The aryl hydrocarbon receptor: a target for breast cancer therapy JO - J Cancer Ther VL - 4 UR - https://doi.org/10.4236/jct.2013.47137 DO - 10.4236/jct.2013.47137 ID - Powell2013 ER - TY - STD TI - Opitz CA, Litzenburger UM, Opitz U, Sahm F, Ochs K, Lutz C, et al. the indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-d-tryptophan upregulates IDO1 in human cancer cells. PLoS One. 2011;6(5):e19823. doi:10.1371/journal.pone.0019823.g008. ID - ref95 ER - TY - JOUR AU - Zhao, S. AU - Kanno, Y. AU - Nakayama, M. AU - Makimura, M. AU - Ohara, S. AU - Inouye, Y. PY - 2012 DA - 2012// TI - Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells JO - Cancer Lett VL - 317 UR - https://doi.org/10.1016/j.canlet.2011.11.025 DO - 10.1016/j.canlet.2011.11.025 ID - Zhao2012 ER - TY - JOUR AU - Zhao, S. AU - Ohara, S. AU - Kanno, Y. AU - Midorikawa, Y. AU - Nakayama, M. AU - Makimura, M. PY - 2013 DA - 2013// TI - HER2 overexpression-mediated inflammatory signaling enhances mammosphere formation through up-regulation of aryl hydrocarbon receptor transcription JO - Cancer Lett VL - 330 UR - https://doi.org/10.1016/j.canlet.2012.11.021 DO - 10.1016/j.canlet.2012.11.021 ID - Zhao2013 ER - TY - JOUR AU - Murray, I. A. AU - Patterson, A. D. AU - Perdew, G. H. PY - 2014 DA - 2014// TI - Aryl hydrocarbon receptor ligands in cancer: friend and foe JO - Nat Rev Cancer VL - 14 UR - https://doi.org/10.1038/nrc3846 DO - 10.1038/nrc3846 ID - Murray2014 ER - TY - JOUR AU - Prud’homme, G. AU - Glinka, Y. AU - Toulina, A. AU - Ace, O. AU - Subramaniam, V. AU - Jothy, S. PY - 2010 DA - 2010// TI - Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0013831 DO - 10.1371/journal.pone.0013831 ID - Prud’homme2010 ER - TY - JOUR AU - Subramaniam, V. AU - Ace, O. AU - Prud’homme, G. J. AU - Jothy, S. PY - 2011 DA - 2011// TI - Tranilast treatment decreases cell growth, migration and inhibits colony formation of human breast cancer cells JO - Exp Mol Pathol VL - 90 UR - https://doi.org/10.1016/j.yexmp.2010.10.012 DO - 10.1016/j.yexmp.2010.10.012 ID - Subramaniam2011 ER - TY - JOUR AU - Howard, G. AU - Schlezinger, J. AU - Hahn, M. AU - Webster, T. PY - 2010 DA - 2010// TI - Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists JO - Environ Health Perspect VL - 118 UR - https://doi.org/10.1289/ehp.0901312 DO - 10.1289/ehp.0901312 ID - Howard2010 ER - TY - JOUR AU - Dubrovska, A. AU - Hartung, A. AU - Bouchez, L. C. AU - Walker, J. R. AU - Reddy, V. A. AU - Cho, C. Y. PY - 2012 DA - 2012// TI - CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling JO - Br J Cancer VL - 107 UR - https://doi.org/10.1038/bjc.2012.105 DO - 10.1038/bjc.2012.105 ID - Dubrovska2012 ER - TY - JOUR AU - Pfaffl, M. PY - 2001 DA - 2001// TI - A new mathematical model for relative quantification in real-time RT-PCR JO - Nucleic Acids Res VL - 29 UR - https://doi.org/10.1093/nar/29.9.e45 DO - 10.1093/nar/29.9.e45 ID - Pfaffl2001 ER - TY - JOUR AU - Taylor, R. T. AU - Wang, F. AU - Hsu, E. L. AU - Hankinson, O. PY - 2009 DA - 2009// TI - Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells JO - Toxicol Sci VL - 107 UR - https://doi.org/10.1093/toxsci/kfn217 DO - 10.1093/toxsci/kfn217 ID - Taylor2009 ER -