Fig. 13
Percent of mice bearing tumors 43 days after receiving orthotopic xenografts of 10,000, 5,000, or 2,500 ALDHhigh or ALDHlow SUM149 cells. The percentage of mice with palpable tumors at day 43 of the experiment presented in Fig. 12 was determined as a measure of tumor initiation efficiency. Mice were given either (a) water + 5 % sucrose (n = 20) or (b) water with doxycycline + 5 % sucrose to induce expression of shAHR (n = 20)