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Table 2 Half maximal effective concentrations (EC50) of two chemotherapeutics in the presence or absence of an AHR inhibitor

From: The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells

Cell population

Drug treatment

Chemotherapeutic EC50 (μM)

ALDHlow

Paclitaxel

0.81

ALDHlow

Paclitaxel + CH

0.56

ALDHhigh

Paclitaxel

1.21

ALDHhigh

Paclitaxel + CH

0.76

ALDHlow

Adriamycin

0.55

ALDHlow

Adriamycin + CH

0.20

ALDHhigh

Adriamycin

1.99

ALDHhigh

Adriamycin + CH

0.60

  1. EC50 values were calculated from the data presented in Fig. 9