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Table 2 Half maximal effective concentrations (EC50) of two chemotherapeutics in the presence or absence of an AHR inhibitor

From: The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells

Cell population Drug treatment Chemotherapeutic EC50 (μM)
ALDHlow Paclitaxel 0.81
ALDHlow Paclitaxel + CH 0.56
ALDHhigh Paclitaxel 1.21
ALDHhigh Paclitaxel + CH 0.76
ALDHlow Adriamycin 0.55
ALDHlow Adriamycin + CH 0.20
ALDHhigh Adriamycin 1.99
ALDHhigh Adriamycin + CH 0.60
  1. EC50 values were calculated from the data presented in Fig. 9