PS1 bait
|
Binding protein
|
Accession number
|
Gene symbol
|
Unique/total peptides
|
Sequence coverage
|
Protein function
|
---|
| | | |
Ca2+(+)
|
Ca2+(-)
|
Ca2+(+)
|
Ca2+(-)
|
Ca2+(+)
|
---|
NT
|
Synaptotagmin 1
|
NP033332
|
SYT1
|
4/4
|
None
|
11.6 %
|
None
|
Calcium sensor for synaptic vesicle fusion and neurotransmitter release
|
L6-7
|
Synaptotagmin 1
|
NP033332
|
SYT1
|
16/26
|
2/2
|
32.1 %
|
5.0 %
| |
L6-7
|
Catenin delta 1
|
NP031641
|
CTNND1
|
17/20
|
25/35
|
20.9 %
|
30.8 %
|
Known presenilin 1 interactor in the brain
|
- The number of peptides identified and the sequence coverage for Syt1 in Ca2+ (-) and Ca2+ (+) conditions is shown. A known PS1 interacting protein, Catenin1 delta, is shown as Ca2+-independent control