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Fig. 5 | BMC Biology

Fig. 5

From: Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals

Fig. 5

Nuclear localisation and transcriptional activity. a Confocal images of fibroblasts transfected with V5-tagged constructs or empty vector control, showing nuclei (blue DAPI), ectopic protein (red) and, in the merged images, actin cytoskeleton (green phalloidin). b Numbers of genes up- and down-regulated by ectopic expression and overlaps between responsive gene sets. The clearest overlap is between TPRX1 and LEUTX down-regulated genes. For stringency criteria, see Methods

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