TY - JOUR AU - Nkwe, David O. AU - Pelchen-Matthews, Annegret AU - Burden, Jemima J. AU - Collinson, Lucy M. AU - Marsh, Mark PY - 2016 DA - 2016/06/23 TI - The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages JO - BMC Biology SP - 50 VL - 14 IS - 1 AB - In HIV-infected macrophages, newly formed progeny virus particles accumulate in intracellular plasma membrane-connected compartments (IPMCs). Although the virus is usually seen in these compartments, it is unclear whether HIV assembly is specifically targeted to IPMCs or whether some viruses may also form at the cell surface but are not detected, as particles budding from the latter site will be released into the medium. SN - 1741-7007 UR - https://doi.org/10.1186/s12915-016-0272-3 DO - 10.1186/s12915-016-0272-3 ID - Nkwe2016 ER -