Fig. 3

Analysis of chimera pair 3 and 4 in dorsal marginal zone (DMZ) explants. a Representative phenotypes of DMZ explants of embryos injected with the indicated mRNAs of chimera pair 3. Wnt5a/Wnt11 Chimera 3.1 inhibits constriction, whereas Wnt11/Wnt5a chimera 3.2 influences constriction and elongation. b Quantification of elongation. c Quantification of constriction. d Representative phenotypes of DMZ explants of embryos injected with the indicated mRNAs of chimera pair 4. Wnt5a/Wnt11 chimera 4.1 does not disturb convergent extension movements, whereas Wnt11/Wnt5a chimera 4.2 inhibits constriction. e Quantification of elongation. f Quantification of constriction. Shown is the frequency of the indicated phenotypes. The superimposed error bars illustrate the variation between N independent experiments. In each experiment, the absolute frequency of the indicated phenotypes was normalized to the control siblings. N: number of biological replicates, n: number of analyzed explants, *** P < 0.001, ** P < 0.01, * P < 0.05 according to Fisher’s exact test, Bars: 200 μm