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Fig. 5 | BMC Biology

Fig. 5

From: Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants

Fig. 5

pbk and rab11fip5 are specific non-canonical Wnt target genes. a Dorsal marginal zone (DMZ) explants were dissected at stage 10.25 and cultivated until siblings reached stage 12. Total RNA was isolated from 30 DMZ explants. Samples with an RNA integrity number value > 8 were analyzed in a microarray or nanostring analysis. b Differential regulation of six spots on the microarray representing three putative xWnt5a target genes. Shown is the average fold change of biological triplicates, the indicated P value is relative to the control morphant-injected explants, ** P < 0.01, * P < 0.05. c Differential regulation of four spots on the microarray representing three putative xWnt11 target genes. Shown is the average fold change of biological triplicates (d). Reevaluation of the six putative non-canonical Wnt target genes by nanostring analysis. Only pbk and rab11fip5 were found to be differentially regulated. Shown is the average fold change of biological triplicates. ** P < 0.01 according to one-sample t test

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