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Table 2 Candidate interactors identified

From: A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large

Bait Interactor SAINT confidence scores Description
Ubiquitous Intestine Seam/hyp7 Neuron
CDC-42 CDC-42 1.00 1.00 1.00 - RHO GTPase
DLG-1 VIT-5 0.60 0.00 1.00 0.33 Vitellogenin
DLG-1 UNC-87 1.00 0.54 0.36 0.61 Maintains structure of myofilaments
DLG-1 DLG-1 1.00 1.00 1.00 1.00 Discs large
DLG-1 VIT-6 0.65 0.00 0.99 0.33 Vitellogenin
DLG-1 ATAD-3 0.99 0.46 0.71 0.49 Mitochondrial protein ATAD3
DLG-1 DIM-1 0.22 0.00 0.04 0.98 Uncharacterized
DLG-1 C39H7.4 0.65 - 0.98 0.33 Uncharacterized
DLG-1 COR-1 0.97 0.33 0.33 0.33 Coronin
DLG-1 LEC-1 0.96 0.06 0.84 0.62 Tandem-repeat type galectin
DLG-1 MAPH-1.1 0.00 - - 0.93 MAP1 homolog
DLG-1 IFB-2 0.66 0.00 0.90 0.93 Intermediate filament protein
DLG-1 F49H12.5 0.56 0.03 0.01 0.93 Thioredoxin domain containing 12
DLG-1 LARP-1 0.00 0.00 0.21 0.92 La-related protein
DLG-1 IFC-2 0.00 0.00 0.91 0.33 Intermediate filament protein
DLG-1 LEC-2 0.90 0.00 0.91 - Tandem-repeat type galectin
DLG-1 R09H10.5 0.89 0.25 0.91 0.32 Uncharacterized
DLG-1 MUP-2 0.90 0.63 0.28 0.66 Muscle contractile protein troponin T
DLG-1 ATN-1 - 0.31 0.90 - Alpha-actinin homolog
DLG-1 GPD-2 0.83 0.01 0.89 0.39 GAPDH
DLG-1 QARS-1 0.00 0.00 0.88 0.39 Glutaminyl (Q) tRNA synthetase
DLG-1 VARS-2 0.00 - 0.00 0.88 Valyl-tRNA synthetase
DLG-1 NMT-1 0.00 - 0.58 0.87 N-myristoyl transferase
DLG-1 MRG-1 0.00 0.00 0.12 0.87 Homolog of MRG15
DLG-1 EPS-8 0.85 0.05 0.82 0.66 Cell signaling adaptor protein
DLG-1 T25F10.6 0.83 0.64 0.22 0.33 Calponin
DLG-1 LEC-4 0.65 - 0.81 0.33 Tandem-repeat type galectin
LET-413 LET-413 1.00 0.86 1.00 - Scribble
LET-413 B0303.3 0.82 0.00 - - Beta-ketothiolase
LET-413 QARS-1 0.82 0.01 - - Glutaminyl (Q) tRNA synthetase
LGL-1 LGL-1 1.00 1.00 1.00 - Lethal giant larvae (Lgl)
LGL-1 PAR-6 0.99 1.00 0.98 - Par-6
LGL-1 PKC-3 0.98 0.97 0.91 - Atypical protein kinase C
LGL-1 QARS-1 0.82 0.00 0.00 - Glutaminyl (Q) tRNA synthetase
  1. Shown are putative interactors identified with a SAINT confidence score >0.8 in at least one of the four tissues examined. Ribosomal proteins are not shown. An expanded copy of this table including spectra counts is shown in Additional file 5: Table S2
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BMC Biology

ISSN: 1741-7007

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