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Table 2 Minimum inhibitory concentrations (μg/mL) for E. coli containing a plasmid encoding N-terminally His-tagged wild-type MCR-1 and MCR-1 T285A

From: Structure of the catalytic domain of the colistin resistance enzyme MCR-1

E. coli + Colistin Polymyxin B
pET28a (empty vector) 0.032 0.032
mcr-1 pET28a 8.0 6.0
mcr-1 T285A pET28a 0.125 0.092