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Table 4 Amino acid position differences between Global and High Local reassortant lineages

From: Frequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread

  

Global reassortant lineage

High Local reassortant lineage

  

N America

SC America

Asia

Australia

M Easta

 

Segment/Position

X (Red)

XII (Dark Red)

III (Light Blue)

XI (Maroon)

XIV (Purple)

VII (Green)

IV (BlueD)

XIII (Orange)

VI (GreenL)

II (Dark Blue)a

Shannon entropy differences

NA/151

D/N/G

D/N/G

D/N

D

D/ G

D

D

D

D

D/N

HA/215

A/S

A/S

S

S

S

S

S

S

S

S

Amino acid differences Global vs. Local

PB2/81

I

I

I

M

M

M

M

M

M

M

PB2/255

I

I

I

V

V

V

V

V

V

V

PB2/392

D

D

D

E

E

E

E

E

E

E

Amino acid differences Local

PB2/221

S

S

A

S

S

A

A

A

A

A

PB2/293

K

K

R

K

K

R

R

R

R

R

PB2/353

K

K

R

K

K

R

R

R

R

R

PB2/560

I/V

I/V

I/V

I

I

V

V

V

V

V

  1. aAlthough assigned High Local by the criteria, it cannot with certainty be regarded as such due to low regional and temporal sampling. It was included for exploratory purposes only
  2. D/N Position was not conserved in this reassortant lineage, and the Shannon entropy of the Global reassortants was not significantly higher in any of the pairwise comparisons
  3. D/ G Only one of the reassortant genomes had a differing amino acid in this position. Shannon entropy of the Global reassortants was not significantly higher in any of the pairwise comparisons
  4. D Position was conserved in these reassortant lineages, but the Shannon entropy of the Global reassortants was not significantly higher in any of the pairwise comparisons