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Table 1 Selection analysis summary

From: The landscape of sex-differential transcriptome and its consequent selection in human adults

Gene group

n

dDNS/dS (MAF > 0.005)

p-value

dStop/dS

(MAF > 0.001)

p-value

Women-specific

26

0.23

0.02

0.27

0.0117

Men-specific

82

0.30

0.0005

0.29

0.0001

Men-specific; no keratin and keratin-associated genes

27

0.28

0.009

0.22

0.026

Moderately women-specific

114

0.16

0.09

0.13

0.0076

Moderately men-specific

49

0.25

0.005

0.07

0.27

Men testis overexpressed

1100

0.238

<0.0001

0.29

<0.0001

  1. dDNS deleterious non-synonymous, dS deleterious synonymous, dSTOP deleterious stop-gain, MAF minor allele frequency