Table 3 List of genes with evolutionary conserved alpha and beta cell-enriched expression
Conserved beta cell-specific genes | |||||
Zebrafish | Log2FC | Mouse | Log2FC | Human | Log2FC |
pdx1 | 5.4 | Pdx1 | 2.9 | PDX1 | 6.4 |
gcgra | 5.1 | Gcgr | 2.6 | GCGR | 4.2 |
ins | 5.7 | Ins2 | 5.4 | INS | 6.9 |
ins | 5.7 | Ins1 | 5.3 | INS | 6.9 |
Conserved alpha cell-enriched genes | |||||
Zebrafish | Log2FC | Mouse | Log2FC | Human | Log2FC |
arxa | 12.1 | Arx | 6.7 | ARX | 6.0 |
nrxn3a | 4.3 | Nrxn3 | 3.1 | NRXN3 | 2.5 |
adrb1 | 2.3 | Adrb1 | 4.3 | ADRB1 | 4.8 |
fap | 2.4 | Fap | 3.0 | FAP | 7.1 |
adcy2a | 6.0 | Adcy2 | 5.7 | ADCY2 | 3.2 |
grap2a | 5.6 | Grap2 | 2.3 | GRAP2 | 2.4 |
ptprz1b | 2.3 | Ptprz1 | 5.0 | PTPRZ1 | 4.6 |
gcgb | 7.4 | Gcg | 5.6 | GCG | 7.5 |
gcga | 5.5 | Gcg | 5.6 | GCG | 7.5 |
adcy7 | 3.5 | Adcy7 | 3.7 | ADCY7 | 2.2 |
adamts18 | 3.5 | Adamts18 | 5.4 | ADAMTS18 | 5.0 |
gata6 | 6.8 | Gata6 | 3.0 | GATA6 | 4.3 |
gc | 4.9 | Gc | 2.5 | GC | 6.6 |
fev | 4.3 | Fev | 5.0 | FEV | 5.5 |
tgfbr2 | 5.6 | Tgfbr2 | 2.6 | TGFBR2 | 2.3 |
kcnc2 | 7.8 | Kcnc2 | 4.0 | KCNC2 | 4.9 |
fgb | 2.9 | Fgb | 2.5 | FGB | 3.0 |
marcksl1a | 5.4 | Marcksl1 | 2.7 | MARCKSL1 | 2.1 |
mrc1b | 5.5 | Mrc1 | 2.2 | MRC1L1 | 2.9 |
tgm2b | 4.2 | Tgm2 | 2.6 | TGM2 | 2.1 |