Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

Table 2 Detoxification, digestive and chemosensory receptor gene families

Gene family	Clan/clade/group	H. armigera	H. zea	Ha-Hz K _a /K _s ^b	B. mori ^c	M. sexta
P450s	M	10	10	0.061	11	16
	2	8	8	0.029	7	8
	3	46	42	0.076	31	45
	4	50	48	0.083	30	34
	Total	114	108		79	103
CCEs	Dietary/detox^a	71 (8)	67 (9)	0.117	52 (8)	67 (9)
	Hormone/semiochemical processing	13 (5)	13 (5)	0.071	13 (5)	16 (6)
	Neuro-developmental	13 (10)	13 (10)	0.022	13 (10)	13 (10)
	Total	97 (23)	93 (24)		78 (23)	96 (25)
GSTs	Delta/epsilon	25	24	0.124	14	16
	Sigma	11	10	0.106	2	8
	Theta	1	1	0.063	1	1
	Zeta	2	2	0	2	2
	Omega	3	3	0.047	4	4
	Total	42	40		23	31
UGTs	UGT33	22	19	0.102	13	16
	UGT40	8	7	0.116	12	9
	Other	16	16	0.114	19	19
	Total	46	42		44	44
ABCs	A	7	7	0.036	7	7
	B	11	11	0.033	9	9
	C	11	11	0.019	11	11
	G	17	17	0.009	16	16
	Other	8	8	0.007	8	11
	Total	54	54		51	54
Serine proteases: major digestive clades	Trypsins^a	51 (15)	46 (15)	0.159	17 (6)	^d
Serine proteases: major digestive clades	Chymotrypsins^a	49 (4)	44 (4)	0.067	28 (3)	^d
Lipases	Acid^a	28 (1)	28 (1)	0.117	32 (1)	^d
Lipases	Neutral^a	61 (10)	60 (9)	0.061	25 (2)	^d
Chemosensory receptor proteins	GRs	213	166	0.292	69	45
	ORs	84	82	0.090	72	73
	OBPs	40	40	0.074	40	45
	CSPs	29	29	0.056	22	21

See Additional file 6: Table S5 and Additional file 4: Sections 1–8 for details of genes, functions and names in each family
^aCatalytically inactive sequences (although not necessarily without function) in parentheses
^bAveraged K _a/K _s for orthologous members of the subfamily
^cFigures based on the official gene sets, with further analysis as described in Additional file 4: Section 13
^dThese figures are not available in the official gene sets at the level of detail required
GR gustatory receptor, OR olfactory receptor, OBP odorant-binding protein, CSP chemosensory protein

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