Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

Table 3 Detoxification gene clades showing enhanced sequence divergence in H. armigera and gene loss in H. zea

Family	Clan/group	Gene number in H. armigera	Gene pairs tested	Significant rate difference (p < 0.05)	H. armigera genes not in H. zea
P450	Detox, clan 3	43	9	3	3
	Detox, clan 4	47	11	5	2
	Other	6	4	2	0
CCE	Detox	55	19	7	4
CCE	Other	16	9	0	0
GST	Detox	36	8	4	2
GST	Other	3	1	0	0

Tajima’s relative rate tests were performed on the numbers listed of H. armigera paralogue gene pairs in the major detoxification groups; for each group examined, the number of pairs showing a significant rate difference is given. Also listed are the numbers of genes in the relevant clades missing in the H. zea assembly. The P450, CCE and GST families are partitioned in these analyses into lineages for which there is empirical evidence for detoxification functions and those for which there is little or no such evidence. More details of the specific genes involved and comparable data for the proteases, lipases and GRs are given in Additional file 4: Table S7

ISSN: 1741-7007