Fig. 2.
From: How driving endonuclease genes can be used to combat pests and disease vectors
The spread of different types of DEGs where homozygote fitness is reduced by 80% (in all examples homing occurs after the gene is expressed). In all panels A–D are recessive DEGs: A, cost is increased mortality in both sexes; B, cost is a reduction in female fecundity and homing only in females; C, as B but homing in both sexes; D, as B but homing in males only; E, as A but now heterozygote fitness half that of homozygote. a The spread of different constructs when the homing rate is 0.9 and the initial frequency of the DEG is 0.01. b Equilibrium population load as a function of homing rate. c Rate of spread from rare as a function of homing rate (increase in frequency per generation)