Fig. 3.
From: Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers
Architecture of SMP-domain containing proteins. a Left: ribbon diagram of the SMP dimer of E-Syt2 (PDBID 4P42). One SMP domain is colored from blue at the N-terminus to red at the C-terminus. Lipid and detergent molecules in the hydrophobic channel are shown in pink. Right: two Mdm12 monomers arranged head-to-tail as observed in the crystal (PDBID 5GYD). Mdm12 and Mmm1 may interact similarly within ERMES. b–d Tethering for E-Syt1, TMEM24, and ERMES, as indicated