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Fig. 2. | BMC Biology

Fig. 2.

From: MultiBac: from protein complex structures to synthetic viral nanosystems

Fig. 2.

Multiprotein complex structural biology. A selection of recent near-atomic structures of MultiBac-produced specimens, determined by X-ray crystallography or electron cryo-microscopy [22,23,24,25,26,27,28,29,30,31]. In the case of mTOR complex 1, heterologous Raptor was produced by using MultiBac and crystallized, and the crystal coordinates fitted into a cryo-EM map of endogenously purified holo-complex in a hybrid approach [31]. Accession numbers from top left to bottom right are EMDB 8166 (α-mannosidase), PDB 5K5S (Ca2+ sensing receptor), PDB 5U1T (separase-securin complex), PDB 5FIB (sphingomyelinase), PDB 5L3X (NELF-AC), PDB 5I6I (acetyl-CoA carboxylase), PDB 5UDL (IFIT1), PDB 5ME3 (Scc2), EMDB 4029 (Pds5B-cohesin complex) and PDB 5FLC (mTOR complex 1)

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