Fig. 5

Effect of miR-105 inhibitor and mimic on the expression of D1 receptor (D1R) in mPFC-cultured neurons. a Levels of D1R in miR-105 inhibitor negative control (miR-105 inhibitor NC) and miR-105 inhibitor-transfected cultured mPFC neurons. Top panel: Immunoblots of D1R protein levels in miR-105 inhibitor NC and miR-105 inhibitor (40 μM)-transfected cultured mPFC neurons. Bottom panel: The average density of D1R bands after the normalization by β-actin protein in miR-105 inhibitor NC and miR-105 inhibitor-transfected-cultured mPFC neurons (n = 5, **P < 0.01, compared to miR-105 inhibitor NC group). b Levels of D1R in miR-105 negative control (miR-105 NC) and miR-105 mimic-transfected-cultured mPFC neurons. Top panel: Immunoblots of D1R protein levels in miR-105 NC and miR-105 mimic (20 μM)-transfected-cultured mPFC neurons. Bottom panel: The average density of the D1R bands after the normalization by β-actin protein in miR-105 NC and miR-105 mimic-transfected-cultured mPFC neurons (n = 5, *P < 0.05, compared to miR-105 NC group). Data are shown as the mean ± SEM