From: Systematic target function annotation of human transcription factors
TF pair classification | Counts | Significant sharing of known functionsc | P value | ||
---|---|---|---|---|---|
Description | Target-function sharing | Target-gene sharing | |||
Unexpected target function similarity | Significanta | Low | 329 | 117 (35.6%) | 0.0010 OR = 1.45 |
Other pairs with low target gene sharing | Not | Low | 42,373 | 11,704 (27.6%) | |
Expected target function similarity | Significanta | Highb | 4583 | 1772 (38.7%) | 7.7 × 10-13 OR = 1.27 |
Other pairs with high target gene sharing | Not | Highb | 26,251 | 8727 (33.2%) |