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Fig. 4 | BMC Biology

Fig. 4

From: A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein eqFP578

Fig. 4

Performance of K-GECO1 in iPSC-CMs. a Representative time course of spontaneous Ca2+ oscillations in iPSC-CMs as imaged using K-GECO1. b Photoactivation of R-GECO1 and c K-GECO1 in iPSC-CMs. Cells with spontaneous activity are colored in red and cells with no spontaneous activity are colored in black. d Combined use of K-GECO1 with ChR2. Illumination with 150 ms of 470-nm light is indicated by blue arrowheads. Supporting numeric data are provided in Additional file 10. A.U. arbitrary units, ChR2 channel rhodopsin-2, iPSC-CM induced pluripotent stem cell–derived cardiomyocyte

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BMC Biology

ISSN: 1741-7007

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