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Fig. 3. | BMC Biology

Fig. 3.

From: Q&A: Trash talk: disposal and remote degradation of neuronal garbage

Fig. 3.

The egress of the exopher. Touch neuron exophers, often including protein aggregates and damaged mitochondria, are extruded into the surrounding hypodermis. In the hypodermis, some exopher contents (possibly mitochondria) can be degraded. However, undegradable contents like mCherry aggregates can be re-extruded from the hypodermis into the body cavity (pseudocoelom). Distant scavenger cells called coelomocytes can take up mCherry from the body cavity, and the mCherry remains within the coelomocytes for the rest of adulthood—possibly analogous to the garbage final resting place—a cellular landfill dump

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