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Fig. 1 | BMC Biology

Fig. 1

From: Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir

Fig. 1

Top 100 gRNA target sites in HIV LTR (a), gag (b), and pol (c) ranked by prevalence (bottom to top) within an alignment of available sequences within group M for each genomic region. The x-axis shows the percentage of all sequences in group M that contain an exact match to the target site. Within each horizontal bar, shading indicates what percentage of sequences with target sites hits belong to each subtype. Inset bar plots show the total number of sequences of each subtype in the alignment

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