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Fig. 4 | BMC Biology

Fig. 4

From: Viral diversity is an obligate consideration in CRISPR/Cas9 designs for targeting the HIV reservoir

Fig. 4

a Number of previously identified target sites from global consensus sequences of group M and subtypes A–C that were present in each patient’s HIV consensus sequence. b Within-host target site conservation for each identified target site using deep-sequence data for 4 patients, summarized using box plots. Black dots indicate outlier target sites (outside 1.5 × IQR), and target sites are grouped and colored according to which consensus sequence they were identified from (the group- or subtype-level consensus from LANL alignments, or from the patient’s HIV consensus sequence)

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