A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0

Table 4 Summary of curated HT-generated regulatory interactions. The total of new RIs is 1048 and those RIs already existing are 107

Complete data uploaded in RegulonDB
	Datasets		Regulatory interactions
TF	Total number of peaks	Sites with missing information	New	Known (added in evidence)	PMID	HT methodology	Reference
ArgR	122	37	67	18	25735747	ChIP-exo, qPCR, and microarray	[28]
ArgR	48	34	10	4	22082910, this work	ChIP-chip and microarray	[29], this work
ArcA	278	143	115	20	24699140	ChIP-chip, qPCR, and microarray	[30]
CsiR	126	0	126	0	28061857	ChIP-seq and RNA-seq	[16]
FNR	224	186	29	9	24699140	ChIP-chip, qPCR, and microarray	[30]
FNR	53	0	29	24	23818864	ChIP-seq and microarray	[31]
Fur	144	87	39	18	25222563	ChIP-exo and RNA-seq	[32]
Fur	134	119	12	3	26670385, this work	ChIP-seq and microarray	[33], this work
Lrp	143	67	68	8	19052235	ChIP-chip and microarray	[34]
Nac	534	0	531	3	28061857	ChIP-seq and RNA-seq	[16]
OmpR	41	31	10	0	26332955	gSELEX	[35]
OmpR	41	30	11	0	28526842	ChIP-exo and RNA-seq	[36]
TrpR	8	7	1	0	22082910, this work	ChIP-chip and microarray	[29], this work

ISSN: 1741-7007