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Fig. 2 | BMC Biology

Fig. 2

From: A role for actomyosin contractility in Notch signaling

Fig. 2

Changes in myosin II activity disrupt bristle patterning. Expression of phospho-insensitive MRLC (sqhAA) or dominant negative zipper (zipDN) constructs in (a) SOP cells only disrupt the final SOP pattern in the notum. Bristle row 2 is shown, control flies express UAS-LifeActRuby. (b) Mean ± SD distance between SOPs in bristle row 2 for the indicated genotypes (dashed, double-headed arrow in control (a)). c Mean ± SD apical diameter for SOPs in bristle row 2 for the indicated genotypes (see bracket in control (a)). d Expression of sqhAA in all notum epithelial cells also disrupts the final SOP pattern in the notum. Bristle rows are indicated by R#, to the right of each panel. e Mean ± SD distance between SOPs in bristle row 1 for the genotypes in (d). Scale bars = 25 μm in all panels. ***p ≤ 0.001; *p ≤ 0.05; ns = not significant by one-way ANOVA with multiple comparisons. (n) = number of spaces (b) or cell diameters (c) measured. N ≥ 4 nota analyzed each genotype

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