Fig. 1
From: Derivation of adult canine intestinal organoids for translational research in gastroenterology
Canine intestinal 3D organoids (enteroids and colonoids) from healthy and inflammatory bowel disease (IBD) dogs. Representative phase contrast images at × 40 magnification of fully differentiated 5–7-day-old duodenal and ileal enteroids and colonoids from healthy dogs and dogs with IBD, as well as gastrointestinal stromal tumor (GIST) and colorectal adenocarcinoma tumor (tumors at × 20 magnification). The structures of enteroids and colonoids from healthy dogs and dogs with IBD appeared comparable. Representative photomicrographs of at least n = 15 (healthy dogs), n = 7 (IBD dogs), and n = 4 (tumors) images of enteroids/colonoids are shown for each location as indicated
