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Fig. 5 | BMC Biology

Fig. 5

From: Inhibiting eukaryotic ribosome biogenesis

Fig. 5

Identified inhibitors target different stages of rRNA processing. A simplified rRNA processing scheme showing processing from 35S pre-rRNA to the mature rRNAs (18S, 5.8S, and 25S) was complemented with examples of inhibitors and their potentially targeted ribosomal maturation steps. The predicted target steps were derived from the altered rRNA processing pattern in the northern blot analysis (Fig. 4, Table 1, and Additional file 1: Figures S10 and S11)

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