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Fig. 6 | BMC Biology

Fig. 6

From: mTORC1/AMPK responses define a core gene set for developmental cell fate switching

Fig. 6

Gene Ontology network analysis of rapamycin/starvation regulation genes. a Approximately 135 genes are induced by both rapamycin and starvation with GO terms for developmental signaling. These were grouped for network association [45]. A major known cAMP signaling protein link involving cAMP synthesis (AcaR, ACA), cyclase regulation (PdkB, RasA), PKA (pPKAc, PKAr), cAMP receptor response (CAR1, Gα2), cAMP turnover (FbxA, CulA, MEK1), and TF target (GtaC) is indicated. ATGs group a class of genes involved in autophagy. Many genes are listed with dictyBase [46, 47] DDB0 genes names. These are clustered based upon their individual annotated properties. b Approximately 300 genes are suppressed by both rapamycin and starvation with GO terms for growth regulation. These were grouped for network association [45]. Two major clusters are noted, for cell division and protein synthesis

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